L3CMOS05100KPA Microscopy Cameras/Microscope Cameras
Product Introduction
The L3CMOS series features C-mount USB3.0 microscopy cameras equipped with Aptina (onsemi) high-sensitivity CMOS sensors and onboard buffer architecture. Under 5 Gbit/s USB3.0 bandwidth, these cameras achieve more stable high frame rate transmission while reducing frame loss and jitter caused by burst data. Resolution coverage spans approximately 2.2–12 MP, suitable for educational, routine scientific research, and general microscopy documentation applications.
The built-in Ultra-Fine color processing engine performs demosaicing, auto exposure/gain control, one-click white balance, and color/gamma/contrast processing on the camera side, reducing host CPU usage while delivering natural and consistent color presentation. The housing features metal (aluminum alloy) CNC precision construction for durability and reliability, while included ToupView/ToupLite software and cross-platform SDK support (Windows/Linux/macOS/Android) facilitate system integration and secondary development.
Key Features
- Sensor: Aptina (onsemi) high-performance CMOS sensors (model dependent) with high sensitivity and low noise
- Resolution range: approximately 2.2–14 MP, covering common microscopy documentation requirements
- Data interface: USB3.0 (5 Gbit/s) high-speed link for smoother real-time preview and acquisition
- Onboard buffer design adjacent to sensor: improves transmission stability and data integrity at high frame rates
- Ultra-Fine color engine: Demosaic, AE/AGC, AWB/one-click white balance, color correction, gamma, brightness/contrast/saturation, LUT
- Bit depth and data: supports 8/12-bit (model dependent) with RAW/Bayer output capability
- Image functions: arbitrary ROI/windowing with digital binning support (2×2/3×3/4×4, model dependent) and image flipping
- Lens interface: Standard C-mount interface compatible with various microscopy/industrial optical systems
- Construction and power: Aluminum alloy CNC housing with USB bus power for simplified cabling and easy deployment (model dependent)
- Software and ecosystem: includes ToupView/ToupLite; provides Windows/Linux/macOS/Android SDK (compatible with DirectShow/TWAIN)
- Typical applications: brightfield/darkfield/low-light microscopy, educational demonstrations and documentation, material/biological sample routine observation
Product Details
| Key Parameters | |
| Model | L3CMOS05100KPA |
| Sensor | AR0521(C) |
| Effective Pixels / Resolution | 5.1M (2592×1944) |
| Frame Rate (Full Resolution) | 15.5 fps@2592×1944; 49.5 fps@1296×972; 97.5 fps@648×486 |
| Shutter Type | Rolling Shutter |
| Color Type | Color |
| Imaging Performance | |
| Pixel Size | 2.2 µm × 2.2 µm |
| Sensor Size | 5.70mm × 4.28mm |
| Diagonal | 0.45" (7.13 mm) |
| Dynamic Range | 73 dB |
| Bit Depth | 8-bit |
| Sensitivity | 18.8 ke-/lux |
| Interface & Mechanical | |
| Data Interface | USB3.0 |
| GPIO | TBD |
| Lens Mount | C-mount |
| Dimensions | TBD |
| Weight | 0.72~0.8Kg |
| Power Supply | USB powered |
| Environment & Certification | |
| Operating Temperature / Humidity | -10 °C ~ 50 °C / 30%~80%RH |
| Storage Temperature / Humidity | -20 °C ~ 60 °C / 10%~60%RH |
| Operating System | Windows/Linux/macOS/Android multi-platform SDK (native C/C++, C#/VB.NET, Python, Java, DirectShow, Twain, etc.) |
| Certification | CE, FCC |
Product Overview
L3CMOS05100KPA is a digital camera specifically designed for microscopic imaging applications, featuring a AR0521(C) high-performance image sensor with the following characteristics:
- Exceptional Imaging Quality: 5.1M (2592×1944) resolution with 2.2 µm × 2.2 µm pixel size, sensor size of 5.70mm × 4.28mm , ensuring clear detail presentation
- High-Speed Imaging Characteristics: Features Rolling Shutter design, supports color imaging, suitable for brightfield, darkfield, phase contrast, fluorescence and other microscopy observation methods
- High-Speed Data Transmission: Utilizes USB3.0 interface with maximum frame rate up to 15.5 fps@2592×1944; 49.5 fps@1296×972; 97.5 fps@648×486 , supporting real-time preview and rapid capture
- Color Reproduction: 8-bit color depth with dynamic range reaching 73 dB , accurately reproducing sample colors
- Ultra-High Sensitivity Performance: Excellent low-light performance with sensitivity of 18.8 ke-/lux , suitable for low-light sample observation
- Optical Compatibility: Standard C-mount interface, compatible with various microscope brands, optional 0.5×/0.63×/1× adapters available
- Compact Design: Overall dimensions of only TBD , weighing 0.72~0.8Kg , powered by USB powered , no additional power supply required
- Software Support: Includes professional microscopy imaging software ToupView, supports Windows/Linux/macOS/Android multi-platform SDK (native C/C++, C#/VB.NET, Python, Java, DirectShow, Twain, etc.) systems, provides measurement, annotation, stitching, focus stacking and other functions, supports C/C++, C#, Python, ImageJ, μManager development environments
Core Performance Indicators
Resolution
5.1M (2592×1944)
Frame Rate
Up to 15.5 fps@2592×1944; 49.5 fps@1296×972; 97.5 fps@648×486
Pixel Size
2.2 µm × 2.2 µm
Data Interface
USB3.0
High-Speed Microscopic Imaging Features
Professional High-Speed Applications
Optimized for biomedical, materials science, and industrial inspection microscopy needs, supports brightfield, darkfield, phase contrast, fluorescence and real-time observation methods
Excellent Color Reproduction
Precise color reproduction algorithms and white balance control ensure accurate and true sample colors, meeting professional needs such as pathological diagnosis
Real-Time Performance
High frame rate and onboard buffer technology ensure smooth real-time preview and rapid image acquisition for dynamic sample observation
Image Processing Capabilities
Supports real-time image enhancement, focus stacking, image stitching and other advanced functions, improving observation effects and imaging quality
Why Choose This High-Speed Camera
The L3CMOS05100KPA high-speed microscopy camera, with its excellent real-time performance, ultra-high sensitivity, and professional software support, is an ideal choice for advanced microscope applications. Whether for dynamic biological processes, high-throughput screening, or precision industrial inspection, it provides fast, accurate, and reliable microscopic image recording and analysis solutions.
L3CMOS05100KPA Product Manual
PDF format, includes detailed technical specifications and dimensional structure
SDK Development Kit
Supports Windows, Linux, macOS and other platforms
3D Model Files
STEP format, for mechanical design integration
Packing List #
Standard accessories and packing details for the L3CMOS large-pixel USB3.0 CMOS cameras
Standard contents
- Carton dimensions: L: 40 cm W: 36 cm H: 36 cm (16 pcs, approx. 12–17 kg/carton)
- Inner box dimensions: L: 16.4 cm W: 16.4 cm H: 9.6 cm (0.72–0.8 kg/box)
- L3CMOS camera body
- High-speed USB3.0 A-to-B gold-plated cable (2.0 m)
- CD (drivers and software, Ø12 cm)
Optional accessories
- Adjustable eyepiece adapters
Dia. 23.2 mm eyepiece to C-mount: 108001/AMA037, 108002/AMA050, 108003/AMA075
Dia. 31.75 mm eyepiece to C-mount: 108008/ATA037, 108009/ATA050, 108010/ATA075 - Fixed eyepiece adapters
Dia. 23.2 mm eyepiece to C-mount: 108005/FMA037, 108006/FMA050, 108007/FMA075
Dia. 31.75 mm eyepiece to C-mount: 108011/FTA037, 108012/FTA050, 108013/FTA075
Product Dimensions #
Outline drawings for the L3CMOS large-pixel USB3.0 CMOS cameras
The L3CMOS series, developed by ToupTek Photonics, delivers ultra-high sensitivity and high-speed USB3.0 microscope imaging. Aptina CMOS sensors provide resolutions from 2.2 MP to 12 MP, paired with a standard C-mount and the USB3.0 data interface for real-time, high-resolution imaging. The solid CNC-machined aluminium body enhances durability and heat dissipation for stable long-term operation.
Key Features
High-performance Aptina sensor
High sensitivity, low noise, and wide dynamic range imaging
Large onboard buffer
Synchronous data transfer and stable high-frame-rate output
High-speed USB3.0 interface
5 Gbps bandwidth for fast, stable video streaming
Ultra-Fine color engine
Accurately reproduces color and reveals fine detail
Performance Highlights
Resolution options
2.2–12 MP
Selectable resolutionFrame rate performance
Up to 50 fps
Higher with ROI croppingPixel size
1.4–2.2 µm
Delivers fine detail and sensitivityExposure range
0.05–2000 ms
Precisely adjustableIn-Depth Product Overview
Ultra-sensitive Aptina CMOS sensors
Uses high-performance Aptina CMOS sensors to deliver very high sensitivity, low noise, and wide dynamic range. The advanced architecture maximizes photoelectric conversion efficiency for clear images even in very low light. Pixel sizes range from 1.4 µm to 2.2 µm to balance fine detail with excellent low-light sensitivity.
Large onboard buffer technology
Built-in large onboard buffer enables synchronous data transfer and stable high-frame-rate output. The buffer prevents frame loss or stutter during continuous high-speed capture, preserving data integrity. Even with heavy data loads, it maintains smooth live preview and reliable acquisition—ideal for long-duration observations of dynamic processes.
USB3.0 ultra-high-speed data transfer
Equipped with a high-speed USB3.0 interface providing up to 5 Gbps bandwidth for fast, stable real-time video transfer. Compared with USB2.0, speed improves more than 10×, fully unleashing the high-resolution sensor performance. Some models reach 50 fps at full resolution, and ROI cropping can deliver even higher frame rates for precise capture of fast dynamics.
Precise Ultra-Fine color engine
Advanced Ultra-Fine image processing reproduces vivid, accurate color while revealing fine detail. The engine improves contrast and clarity so delicate sample structures remain visible—ideal for pathology, materials analysis, and other color-critical applications.
Industrial-grade rugged construction
The CNC-milled aluminium housing delivers structural strength and efficient passive cooling with no moving parts—eliminating vibration and reducing noise. Consistent thermal management keeps the sensor within its optimal range for reliable long-term imaging, while the metal enclosure offers strong electromagnetic shielding.
Applications
Application examples of the L3CMOS series in microscope imaging
Key Advantages of the L3CMOS Series
Ultra-high sensitivity
Powered by Aptina CMOS sensors
USB3.0 high speed
5 Gbps data throughput
Large buffer
Delivers stable high-frame-rate output
Accurate color reproduction
Ultra-Fine color engine
High frame rate
Up to 50 fps full-resolution imaging
Aluminium alloy body
CNC one-piece design
Cross-platform SDK
Rapid integration
Extensive model range
2.2–12 MP options